The mission of every Infectious Awareables tie is to generate interest, discussion, even excitement about serious public health issues such as this silk Diabetes tie in black. Believing that humor can be a powerful educational tool, Infectious Awareables neckties take an atypical, slightly irreverent approach to some very serious subjects. Shop and take pride in knowing that a portion of the proceeds will be donated to disease research/education. "Start the Conversation" Diabetes. This creative pattern features complex INSULIN molecules accented by random – gulp - SUGAR cubes, symbolizing the balance required for the critical task of regulating carbohydrate metabolism. Diabetes and the obesity that is often an accompanying risk factor has grown to epidemic proportions. It is now the seventh leading cause of death in the U.S. A back-of-tie "Awareness Note" and a source citation are incorporated in the pattern design, which reads: "DIABETES is a metabolic disease characterized by high levels of blood SUGAR caused by either lack of the hormone INSULIN or inability of cells to utilize insulin produced. Obesity is often a major cause of the imbalance. Management typically includes weight loss, healthy diet, physical exercise and monitoring." Note: IA contributes a portion of proceeds to research, education or support associated with important non-profit public health agencies and organizations.